MIS 301 Introduction to Management Information Systems

Course syllabus for MIS 301 Introduction to Management Information Systems Course description: Provides an overview of business data processing and management information systems. Covers introductory concepts of computer technology, nature of computer application in business systems analysis techniques, and problem solving. Includes introduction to and use of Basic computer programming for business related problems

Low Mass Companions for Five Solar-Type Stars from the Magellan Planet Search Program

We report low mass companions orbiting five Solar-type stars that have emerged from the Magellan precision Doppler velocity survey, with minimum (Msini) masses ranging from 1.2 to 25 Mjup. These nearby target stars range from mildly metal-poor to metal-rich, and appear to have low chromospheric activity. The companions to the brightest two of these stars have previously been reported from the CORALIE survey. Four of these companions (HD 48265-b, HD 143361-b, HD 28185-b, HD 111232-b) are low-mass Jupiter-like planets in eccentric intermediate and long-period orbits. On the other hand, the companion to HD 43848 appears to be a long period brown dwarf in a very eccentric orbit.Comment: Accepted for publication on ApJ, 26 pages, 10 figures, 7 table

Ground-based detections of thermal emission from CoRoT-1b and WASP-12b

We report a new detection of the H-band thermal emission of CoRoT-1b and two confirmation detections of the Ks-band thermal emission of WASP-12b at secondary eclipses. The H-band measurement of CoRoT-1b shows an eclipse depth of 0.145%\pm0.049% with a 3-{\sigma} percentile between 0.033% - 0.235%. This depth is consistent with the previous conclusions that the planet has an isother- mal region with inefficient heat transport from dayside to nightside, and has a dayside thermal inversion layer at high altitude. The two Ks band detections of WASP-12b show a joint eclipse depth of 0.299%\pm0.065%. This result agrees with the measurement of Croll & collaborators, providing independent confirmation of their measurement. The repeatability of the WASP-12b measurements also validates our data analysis method. Our measurements, in addition to a number of previous results made with other telescopes, demonstrate that ground-based observations are becoming widely available for characterization of atmospheres of hot Jupiters.Comment: 20 pages, including 8 figures and 1 table. Accepted for publication in Ap

SPITZER: Accretion in Low Mass Stars and Brown Dwarfs in the Lambda Orionis Cluster

We present multi-wavelength optical and infrared photometry of 170 previously known low mass stars and brown dwarfs of the 5 Myr Collinder 69 cluster (Lambda Orionis). The new photometry supports cluster membership for most of them, with less than 15% of the previous candidates identified as probable non-members. The near infrared photometry allows us to identify stars with IR excesses, and we find that the Class II population is very large, around 25% for stars (in the spectral range M0 - M6.5) and 40% for brown dwarfs, down to 0.04 Msun, despite the fact that the H(alpha) equivalent width is low for a significant fraction of them. In addition, there are a number of substellar objects, classified as Class III, that have optically thin disks. The Class II members are distributed in an inhomogeneous way, lying preferentially in a filament running toward the south-east. The IR excesses for the Collinder 69 members range from pure Class II (flat or nearly flat spectra longward of 1 micron), to transition disks with no near-IR excess but excesses beginning within the IRAC wavelength range, to two stars with excess only detected at 24 micron. Collinder 69 thus appears to be at an age where it provides a natural laboratory for the study of primordial disks and their dissipation.Comment: ApJ, in pres

Mast Cell Regulation of the Immune Response

Mast cells are well known as principle effector cells of type I hypersensitivity responses. Beyond this role in allergic disease, these cells are now appreciated as playing an important role in many inflammatory conditions. This review summarizes the support for mast cell involvement in resisting bacterial infection, exacerbating autoimmunity and atherosclerosis, and promoting cancer progression. A commonality in these conditions is the ability of mast cells to elicit migration of many cell types, often through the production of inflammatory cytokines such as tumor necrosis factor. However, recent data also demonstrates that mast cells can suppress the immune response through interleukin-10 production. The data encourage those working in this field to expand their view of how mast cells contribute to immune homeostasis

High energy solar neutrinos and p-wave contributions to ^3He(p,\nue^+)^4He

High energy solar neutrinos can come from the hep reaction ^3He(p,\nue^+)^4He with a large end point energy of 18.8 MeV. Understanding the hep reaction may be important for interpreting solar neutrino spectra. We calculate the contribution of the axial charge transition $^3P_0\to ^1S_0$ to the hep thermonuclear S factor using a one-body reaction model involving a nucleon moving in optical potentials. Our result is comparable to or larger than previous calculations of the s-wave Gamow Teller contribution. This indicates that the hep reaction may have p-wave strength leading to an enhancement of the S factor.Comment: 4 pages, 1 ps figure, very minor changes, Phys. Rev. C in pres

Quantum Gravity Hamiltonian for Manifolds with Boundary

In canonical quantum gravity, when space is a compact manifold with boundary there is a Hamiltonian given by an integral over the boundary. Here we compute the action of this `boundary Hamiltonian' on observables corresponding to open Wilson lines in the new variables formulation of quantum gravity. In cases where the boundary conditions fix the metric on the boundary (e.g., in the asymptotically Minkowskian case) one can obtain a finite result, given by a `shift operator' generating translations of the Wilson line in the direction of its tangent vector. A similar shift operator serves as the Hamiltonian constraint in Morales-T\'ecotl and Rovelli's work on quantum gravity coupled to Weyl spinors. This suggests the appearance of an induced field theory of Weyl spinors on the boundary, analogous to that considered in Carlip's work on the statistical mechanics of the 2+1-dimensional black hole.Comment: 17 pages in LaTeX format, vastly improved versio

Apollo Lightcraft project

The detailed design of a beam-powered transatmospheric vehicle, the Apollo Lightcraft, was selected as the project for the design course. The principal goal is to reduce the LEO payload delivery cost by at least three orders of magnitude below the Space Shuttle Orbiter in the post 2020 era. The completely reusable, single-stage-to-orbit shuttlecraft will take off and land vertically, and have a reentry heat shield integrated with its lower surface. At appropriate points along the launch trajectory, the combined cycle propulsion system will transition through three or four airbreathing modes, and finally use a pure rocket mode for orbital insertion. The objective for the Spring semester propulsion source was to design and perform a detailed theoretical analysis on an advanced combined-cycle engine suitable for the Apollo Lightcraft. The preliminary theoretical analysis of this combined-cycle engine is now completed, and the acceleration performance along representative orbital trajectories was simulated. The total round trip cost is $3430 or$686 per person. This represents a payload delivery cost of $3.11/lb, which is a factor of 1000 below the STS. The Apollo Lightcraft concept is now ready for a more detailed investigation during the Fall semester Transatmosphere Vehicle Design course

Multi-omic analysis elucidates the genetic basis of hydrocephalus.

We conducted PrediXcan analysis of hydrocephalus risk in ten neurological tissues and whole blood. Decreased expression of MAEL in the brain was significantly associated (Bonferroni-adjusted p < 0.05) with hydrocephalus. PrediXcan analysis of brain imaging and genomics data in the independent UK Biobank (N = 8,428) revealed that MAEL expression in the frontal cortex is associated with white matter and total brain volumes. Among the top differentially expressed genes in brain, we observed a significant enrichment for gene-level associations with these structural phenotypes, suggesting an effect on disease risk through regulation of brain structure and integrity. We found additional support for these genes through analysis of the choroid plexus transcriptome of a murine model of hydrocephalus. Finally, differential protein expression analysis in patient cerebrospinal fluid recapitulated disease-associated expression changes in neurological tissues, but not in whole blood. Our findings provide convergent evidence highlighting the importance of tissue-specific pathways and mechanisms in the pathophysiology of hydrocephalus